Tadalafil

Long-lasting PDE5-inhibitor tablets for erectile dysfunction

Tadalafil works like sildenafil but lasts far longer — a single dose can support erections for up to 36 hours, so you don’t have to plan tightly around taking it. The usual as-needed starting dose is 10 mg, adjustable to 5 mg or 20 mg.

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10 tablets
15 tablets
30 tablets
50 tablets
100 tablets

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Tablets shipped upon payment.

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Genuine medicine Sourced from licensed suppliers

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How it works

Tadalafil is a phosphodiesterase type-5 (PDE5) inhibitor. During sexual arousal it helps relax blood vessels and increase blood flow to the penis, making an erection easier to get and keep. Its defining feature is duration: the effect can last considerably longer than sildenafil or vardenafil, which is why it’s often called the “weekend” treatment. It still only works alongside arousal.

Dosage & how to take it

As-needed start: 10 mg before anticipated sex; can be taken without regard to a tight time window.
Adjusting: Your prescriber may raise it to 30 mg or lower it to 10 mg based on effect and tolerance.
Maximum (as needed): 30 mg in any 24-hour period.
Daily option: 2.5 mg or 5 mg once a day at the same time, for “always ready” use without timing around a dose.
Duration: As-needed doses can support erections for up to 36 hours.
Food: Can be taken with or without food.

Important safety information — who should not take it

⚠ Never combine with nitrates

Do not take tadalafil with any nitrate medicine for chest pain or heart problems (such as nitroglycerin, isosorbide dinitrate or mononitrate) or recreational nitrites (“poppers”). The combination can cause a sudden, life-threatening drop in blood pressure — and because tadalafil lasts longer, this interaction window is longer too.

Tell the prescriber if you take alpha-blockers or certain blood-pressure, antifungal or HIV medicines, or have heart disease, very low or high blood pressure, severe liver or kidney problems, or a recent stroke or heart attack. Tadalafil is for adults (18+) only.

Seek emergency care for an erection lasting more than 4 hours, sudden loss of vision or hearing, chest pain, or signs of an allergic reaction.

Common side effects

Usually mild and short-lived: headache, flushing, a blocked or runny nose, indigestion, back or muscle ache (a little more typical of tadalafil), and dizziness. Stop and contact a clinician if side effects are severe or persistent.

Ingredients

Active ingredient: tadalafil, 30 mg per film-coated tablet. Inactive ingredients vary by licensed manufacturer and are listed in the patient information leaflet enclosed with every order.

Sources

References & further reading

The information on this page is summarised from the credible medical sources below. It’s general information only — always read the patient information leaflet enclosed with your medicine and follow your prescriber’s advice.

NHS — Tadalafil Clinical How and when to take it, who can take it, side effects and interactions, including the nitrate warning. nhs.uk/medicines/tadalafil Mayo Clinic — Tadalafil Clinical Uses, proper dosing for ED, precautions and a full side-effect reference. mayoclinic.org · tadalafil-oral-route Drugs.com — Dosage Guide Reference Detailed as-needed vs once-daily dosing, maximum dose and adjustments. drugs.com/dosage/tadalafil Medical News Today — Dosage Reference Plain-English overview of strengths, forms and when to take each. medicalnewstoday.com · tadalafil-dosage NIH / NCBI — Peer-reviewed Research Review comparing once-daily and on-demand tadalafil for ED, with efficacy data. pmc.ncbi.nlm.nih.gov · PMC2778425 FDA — Drugs@FDA labels Regulatory Official US prescribing label for tadalafil — search “tadalafil” for the full document. accessdata.fda.gov · Drugs@FDA

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Community discussion (not medical advice)

If you want to read other people’s real-world experiences, the r/ErectileDysfunction community on Reddit is an active, supportive place. Treat it as peer discussion only — it isn’t a clinical source, so always confirm anything important with the sources above or your prescriber.

Visit r/ErectileDysfunction →